Intellectual Property India Publishes Patent Application for “green Synthesis And Characterization Of Transition Metal Complexes Of Hydrazone/Oxime Derivatives From Allium Sativum (garlic) And Their Pharmacological Activity”

MUMBAI, India, Aug. 17 -- Intellectual Property India has published a patent application (202621077535 A) filed by Dr. Pallavi M. Patil; Mr. Mayur Sanjay Tekade; Dr. Pravin D. Chaudhari; Dr. Vitthal V. Chopade; and P. E. Societys Modern College Of Pharmacy, Nigdi, Pune. on June 23, 2026, for “green Synthesis And Characterization Of Transition Metal Complexes Of Hydrazone/Oxime Derivatives From Allium Sativum (garlic) And Their Pharmacological Activity”.

Inventors include Dr. Pallavi M. Patil; Mr. Mayur Sanjay Tekade; Dr. Pravin D. Chaudhari; and Dr. Vitthal V. Chopade.

The application for the patent was published on August 14, 2026, under issue no. 33/2026.

Abstract: The present invention pertains to the field of medicinal chemistry, coordination chemistry, and pharmaceutical sciences. Specifically, the invention relates to a novel green synthesis methodology for the preparation of transition metal complexes—comprising Copper [Cu(II)], Cadmium [Cd(II)], Cobalt [Co(II)], and Nickel [Ni(II)]— with hydrazone/oxime Schiff base ligands derived from bioactive sulfur-containing compounds isolated from Allium sativum (garlic). The invention further encompasses the structural characterization of these novel metal chelates using a comprehensive battery of spectroscopic and analytical techniques, and their evaluation for significant pharmacological activities including antioxidant, anticoagulant, anticancer (cytotoxicity against MCF-7 human breast cancer cell line), and anti- inflammatory activities.

Disclaimer: Curated by HT Syndication.