MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202641024609 A) filed by Vellore Institute Of Technology, Vellore, Tamil Nadu, on March 2, for 'a composition and method for preparing dual-antibiotic bilosome nanogel for infected wounds.'
Inventor(s) include Dr. Natarajan Chandrasekaran; Dr. George Priya Doss C; Mr. Mohanraj Gopikrishnan; and Ms. Disha Pramanick.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "The present disclosure proposes a hybrid bilosome-nanogel composition (100) adapted to deliver levofloxacin and gentamicin in a sustained and localized manner for infected wounds and biofilm-associated wound infections. The composition (100) comprises at least one soy lecithin (102), cholesterol (104), at least one bile salt (106), levofloxacin (108), gentamicin (110), sodium alginate (112), Tween-80 (113), hydroxypropyl methylcellulose (HPMC) (114), and sterile distilled water (115). The composition (100) provides sustained and localised delivery of levofloxacin and gentamicin at a wound site by maintaining prolonged residence and controlled release at the wound interface, for use in biofilm-associated infected wounds caused by Pseudomonas aeruginosa. The composition (100) improves physicochemical stability of the dual-antibiotic formulation under storage and environmental conditions through bile salt-stabilized vesicular structure and gel embedding. The composition (100) enables improved wound healing outcomes by supporting faster bacterial clearance, improved granulation, and re-epithelialization through sustained localized antimicrobial action."
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