MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202611026857 A) filed by Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, on March 7, for 'a method and semi-synthetic compounds for enhancing pharmacokinetic and therapeutic properties of plant-derived bioactive molecules.'

Inventor(s) include Dr. Manish Pathak.

The application for the patent was published on May 1, under issue no. 18/2026.

According to the abstract released by the Intellectual Property India: "The present invention relates to a method and semi-synthetic compounds for enhancing pharmacokinetic and therapeutic properties of plant-derived bioactive molecules. The method comprises selecting a plant-origin bioactive compound exhibiting pharmacological activity and identifying predetermined functional groups responsible for pharmacokinetic limitations. Site-specific medicinal-chemistry modifications are performed to generate semi-synthetic derivatives that preserve the core pharmacophore while improving bioavailability, metabolic stability, and therapeutic efficacy. The resulting semi-synthetic compounds exhibit reduced susceptibility to enzymatic degradation, prolonged systemic exposure, and improved safety profiles compared to unmodified natural compounds."

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