MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202611008933 A) filed by Swami Vivekananda Subharti University, Meerut, Uttar Pradesh, on Jan. 29, for 'a method and system for data-driven design, synthesis optimization, and formulation of hybrid sulfonamide-thiazolidin-4-one therapeutic compounds.'
Inventor(s) include Dr. Aadesh Kumar; and Dr. Nidhi Dhama.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to an integrated method, system, and pharmaceutical composition for developing hybrid sulfonamide-thiazolidin-4-one derivatives exhibiting dual antimicrobial and anti-inflammatory activity. The invention provides an AI/ML-assisted workflow, applied only where required, to enable rational molecular design, synthesis selection, biological validation, and formulation optimization of hybrid compounds. A plurality of candidate structures combining sulfonamide and thiazolidin-4-one pharmacophores is generated and prioritized based on predicted biological efficacy, synthetic feasibility, and physicochemical properties. Selected candidates are synthesized using one-pot or microwave-assisted protocols and biologically validated through antimicrobial and anti-inflammatory assays. Biologically validated compounds are formulated into pharmaceutically acceptable compositions, including oral solid dosage forms and topical formulations."
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