MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202611025966 A) filed by Noida Institute Of Engineering & Technology, Greater Noida, Uttar Pradesh, on March 5, for 'a method for formulation and evaluation of phytoconstituent-loaded microcapsules for anxiety treatment.'
Inventor(s) include Dr Monika; Dr Rupa Mazumder; Mr Shreyansh Singh; Ms Sonia Chauhan; Dr Chandana Majee; and Mr Anmol Dogra.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "Disclosed herein is a method (100) for formulation and evaluation of phytoconstituent-loaded microcapsules for anxiety treatment involves procuring a phytoconstituent drug along with pharmaceutically acceptable excipients (102), followed by conducting comprehensive preformulation studies (104) to characterize the drug and excipients. The method further includes optimization of formulation parameters (106) employing a Box-Behnken experimental design. Sustained-release microcapsules are then prepared (108) by dispersing the phytoconstituent with a suitable polymer in an aqueous medium, forming a homogeneous dispersion, and subjecting it to ionotropic cross-linking in calcium chloride solution to obtain hardened microcapsules. The prepared microcapsules are evaluated (110) for particle size, polydispersity index, surface morphology, production yield, drug entrapment efficiency, and in vitro drug release. Release kinetics are analyzed (112) using zero-order, first-order, Higuchi, and Korsmeyer-Peppas models, and the anxiolytic efficacy of the optimized formulation is assessed in vivo (114) using an elevated plus maze model."
Disclaimer: Curated by HT Syndication.
