MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202611051103 A) filed by Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, on April 22, for 'a ph-responsive ligand-functionalized carboxymethylated nano-carrot fiber drug delivery system for targeted quercetin anticancer therapy.'
Inventor(s) include Dr Dharmendra Kumar; and Dr Pramod Kumar Sharma.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a pH-responsive, ligand-functionalized nano-structured carrot fiber nanocarrier system for targeted anticancer drug delivery. The system comprises nano-fibrillated carrot cellulose fibers having particle dimensions in the range of approximately 100 300 nm, chemically modified through controlled carboxymethylation to achieve a degree of substitution between 0.4 and 0.8. The modified nanofibers encapsulate the bioactive compound quercetin, a hydrophobic flavonoid with proven anticancer activity. Surface functionalization with targeting ligands selected from folic acid, hyaluronic acid, peptides, or receptor-binding biomolecules enables receptor-mediated uptake by cancer cells. The nanocarrier matrix exhibits pH-responsive swelling and controlled diffusion-mediated drug release in acidic tumor microenvironments (pH 5.5 6.8), thereby enabling selective and sustained delivery of quercetin to malignant tissues. The formulation improves quercetin solubility, bioavailability, cellular uptake, and therapeutic efficacy while reducing systemic toxicity."
Disclaimer: Curated by HT Syndication.
