MUMBAI, India, Jan. 23 -- Intellectual Property India has published a patent application (202641001496 A) filed by Meenakshi Academy Of Higher Education and Research; and Meenakshi Ammal Dental College And Hospital, Chennai, Tamil Nadu, on Jan. 6, for 'a process for preparing a neuroregenerative bioactive hydrogel for lingual nerve regeneration.'
Inventor(s) include Dr. P. Bhuvaneshwari; and Dr. Rhenius Jonathan A.
The application for the patent was published on Jan. 23, under issue no. 04/2026.
According to the abstract released by the Intellectual Property India: "The present invention discloses a method for preparing a neuroregenerative composition for handling lingual nerve injury following third molar extraction. The method comprises synthesizing a gelatin methacryloyl (GelMA) hydrogel matrix by dissolving gelatin in phosphate-buffered saline (PBS), reacting with methacrylic anhydride under stirring, followed by dialysis, lyophilization, reconstitution in PBS, and photopolymerization to obtain a crosslinked GelMA hydrogel. Dental pulp stem cells (DPSCs) are isolated from extracted and discarded human third molars by enzymatic digestion using collagenase type I and dispase, followed by centrifugation and culturing in Dulbecco's Modified Eagle Medium supplemented with fetal bovine serum and antibiotics to obtain viable DPSCs. Citicoline is prepared by dissolving in sterile PBS. The neuroregenerative composition is formulated by mixing the GelMA hydrogel matrix, DPSCs, and citicoline solution under sterile conditions, homogenizing the mixture, and loading into a sterile syringe to obtain a bioactive composition suitable for promoting lingual nerve regeneration."
Disclaimer: Curated by HT Syndication.
