MUMBAI, India, Jan. 23 -- Intellectual Property India has published a patent application (202511125560 A) filed by Swami Rama Himalayan University, Dehradun, Uttarakhand, on Dec. 12, 2025, for 'a system for the management of clinically significant anti-m alloantibodies.'

Inventor(s) include Manish Raturi; Yashaswi Dhiman; and Dushyant Singh Gaur.

The application for the patent was published on Jan. 23, under issue no. 04/2026.

According to the abstract released by the Intellectual Property India: "The invention relates to immunohematological diagnostics and donor selection for transfusion medicine. It comprises an antibody detection module that performs column agglutination tests using three-red cell and extended 11-red cell panels to assess variable M antigen expression, a reagent processing unit that differentiates IgM from IgG through selective dithiothreitol treatment, and an automated blood grouping and crossmatch system for capturing agglutination reactions under ambient and 37 C conditions. Additionally, an institutional donor registry with an inventory management and transfusion coordination interface electronically stores and queries pre-phenotyped donor data to identify M antigen-negative blood units, thereby ensuring efficient, reliable compatibility testing and optimal management of clinically significant anti-M alloantibodies."

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