MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541122314 A) filed by Dayananda Sagar Academy Of Technology & Management, Bengaluru, Karnataka, on Dec. 5, 2025, for 'adaptive multi-modal therapeutic system for chronic venous insufficiency with real-time hemodynamic monitoring.'
Inventor(s) include Dr. Mano Paul P; Sahana Sharma M; Priyanka R; Priyanka V Gudada; Abhinav; Vikram S Gali; G Surya Karthik; Yagnesh Reddy Bolla; Aditya G. Mundase; and Medisetty Sathya Kshitij.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to an adaptive multi-modal therapeutic system for chronic venous insufficiency comprising a compression sleeve (1) with six graduated pneumatic chambers (2a-2f) providing 20-80 mmHg pressure, four thermal zones (26) operating at 38-43 C with PID control, and four vibration actuators (27) delivering 10-150 Hz frequency. The system integrates a comprehensive sensor array including PPG module (17) with dual-wavelength LEDs at 660nm and 940nm sampling at 200 Hz, temperature sensors (18), pressure transducers (12), ultrasonic sensors (19), bioimpedance electrodes (20), and accelerometer (21). An ESP-32 microcontroller (23) executes machine learning algorithms (34) combining Random Forest and XGBoost models processing 23 parameters to generate 89 derived features, achieving 89% prediction accuracy. A three-layer safety architecture (67, 68, 69) comprises hardware failsafes, embedded software monitors with 50ms response, and LSTM neural network (45) providing 15-30 minute advance warning. The system delivers synchronized cardiac cycle-based therapy achieving 47% improvement in venous return velocity and 52% improvement in venous filling time with 94% patient compliance."
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