MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202611009861 A) filed by Swami Vivekananda Subharti University, Meerut, Uttar Pradesh, on Jan. 30, for 'an intelligent and self-protective multi-layer biodegradable nanoparticle system for secure oral insulin delivery.'
Inventor(s) include Shivangi Sangal.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "The present invention provides an intelligent, secure, and self-protective multi-layer oral insulin nanoparticle system designed to overcome the physiological barriers that limit effective oral insulin delivery. The system comprises a stabilized insulin core surrounded by a biochemical protection matrix, a gastric-resistant self-healing layer that preserves structural integrity under acidic conditions, an enzyme-responsive release-control layer that selectively degrades in the intestinal environment, and a mucus-penetrating immune-stealth outer layer that facilitates efficient epithelial transport. These synergistic layers protect insulin from gastric degradation, prevent premature enzymatic breakdown, and enable controlled, site-specific release triggered by intestinal pH and enzyme concentrations. The nanoparticles can be incorporated into capsules, tablets, granules, or suspensions to provide a non-invasive alternative to injectable insulin. The disclosed system significantly enhances insulin bioavailability, ensures predictable therapeutic performance, and improves patient compliance by enabling safe, stable, and physiologically synchronized oral insulin administration."
Disclaimer: Curated by HT Syndication.
