MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202641049659 A) filed by Anurag University, Hyderabad, Telangana, on April 18, for 'benzalkonium-based liposomal delivery of vincristine.'
Inventor(s) include Dr. Mani Sharma; and Dr. Kotipalli Rama Satya Sri.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a nanotechnology-based liposomal drug delivery (112) system for enhanced anticancer therapy. The formulation comprises benzalkonium-derived amphiphilic lipid (102), cholesterol, DSPE-PEG400, and vincristine, prepared using a thin film hydration method. The developed liposomal system exhibits improved solubility, stability, and controlled release of vincristine, thereby enhancing bioavailability and therapeutic efficacy. The incorporation of functional lipids facilitates targeted delivery and increased cellular uptake in cancer cells while minimizing systemic toxicity. The formulation is characterized by optimal particle size, zeta potential, and morphological properties, ensuring stability and efficient drug encapsulation. Further, in vitro anticancer evaluation (110) demonstrates significant cytotoxic activity against breast cancer cell lines. The invention provides a biocompatible and efficient platform for targeted drug delivery and can be extended to other anticancer agents for improved clinical outcomes."
Disclaimer: Curated by HT Syndication.
