MUMBAI, India, July 11 -- Intellectual Property India has published a patent application (202511060327 A) filed by Sher-E-Kashmir University Of Agricultural Sciences And Technology Of Kashmir, Srinagar, Jammu and Kashmir, on June 24, for 'biodegradable, biocompatible, elastic bilayered 3d-printed scaffold patch mimicking-periosteum for enhanced bone regeneration (osteothrive periosteum patch).'

Inventor(s) include Dr. Mudasir Bashir Gugjoo; Aasim Hussain Zarger; Auqib Hamid; Mursaleen Rashid; Maddinni Akhil; Sushanthakumara Patila; Gunukula Manideep; and Amatul Muhee.

The application for the patent was published on July 11, under issue no. 28/2025.

According to the abstract released by the Intellectual Property India: "The present invention relates to a biodegradable, biocompatible, and elastic bilayered periosteum-mimicking universal ready-to-use scaffold patch specifically designed for bone regeneration. The bi layered scaffold patch comprises; an outer fibrous-like layer for mechanical support and suturability; and an inner cambium-like layer for promoting cell attachment and bone integration. Central to the innovation is a novel proprietary resin utilized first time for bone tissue engineering applications via LCD-based 3D printing. This high-elongation, biocompatible resin is uniquely premixed with 15% nanocement, comprising nanohydroxyapatite and calcium sulphate hemihydrate, to enhance bone matrix synthesis (osteoconductivity) and mechanical strength. Post-printing gelatin functionalization on inner layer further enhances cellular adhesion and bioactivity (osteoinductivity). The suturable scaffold patch is designed to act as a universal scaffold patch that conforms to curved bone surfaces and varied bone defects, supports cell loading, and undergoes approximately 17% degradation within 6 weeks, making it highly suitable for critical-sized bone defects, non-union fractures, and advanced bone tissue engineering. The use of LCD 3D printing allows for economic high-precision fabrication and patient-specific customization, representing a significant advancement in scaffold patch design and biomaterial application."

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