MUMBAI, India, Aug. 29 -- Intellectual Property India has published a patent application (202517073643 A) filed by Bicara Therapeutics Inc., Boston, on Aug. 1, for 'combination therapy and related methods.'

Inventor(s) include Salazar, Rachel; Nair, Pradip; Boreddy, Srinivas Reddy; Pandey, Prashant Kumar; and Kumara M. V, Prashantha.

The application for the patent was published on Aug. 29, under issue no. 35/2025.

According to the abstract released by the Intellectual Property India: "Provided herein are methods comprising the use of KRAS (e.g., hKRAS) inhibitors in combination with an agent(s) that specifically binds to EGFR (e.g., hEGFR) and TGF (e.g., hTGF), as well as compositions and kits comprising the same. The methods provided herein are useful in methods of treating cancer, (e.g., KRAS (e.g., hKRAS) variant cancers). Further provided herein are combination regimens, combination compositions, pharmaceutical compositions, and kits comprising a KRAS (e.g., hKRAS) inhibitor and an agent(s) that specifically binds to EGFR (e.g., hEGFR) and TGF (e.g., hTGF)."

The patent application was internationally filed on Feb. 06, 2024, under International application No.PCT/US2024/014543.

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