Intellectual Property India Publishes Patent Application for 'Combinations Of Retinaldehyde Dehydrogenase 1 (RALDH1) Inhibitors And Immunostimulators And Methods Using Same' Filed by The Trustees Of The University Of Pennsylvania; and Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, National Institutes Of Health

MUMBAI, India, Nov. 14 -- Intellectual Property India has published a patent application (202517095866 A) filed by The Trustees Of The University Of Pennsylvania; and Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, National Institutes Of Health, Philadelphia, on Oct. 6, for 'combinations of retinaldehyde dehydrogenase 1 (raldh1) inhibitors and immunostimulators and methods using same.'

Inventor(s) include Haldar, Malay; Rai Bantukallu, Ganesha; Yang, Shyh Ming; Martinez, Natalia Julia; Simeonov, Anton; Zakharov, Alexey Vladimirovich; and Yasgar, Adam Scott.

The application for the patent was published on Nov. 14, under issue no. 46/2025.

According to the abstract released by the Intellectual Property India: "The present disclosure relates in part to methods of treating a solid tumor in a subject in need thereof, the method comprising administering to the subject a retinaldehyde dehydrogenase 1 (RALDH1) inhibitor and an immunostimulator. The present disclosure further relates to pharmaceutical compositions comprising an RALDH1 inhibitor and an immunostimulator."

The patent application was internationally filed on Mar. 15, 2024, under International application No.PCT/US2024/020160.

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