MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202611008834 A) filed by Swami Vivekananda Subharti University, Meerut, Uttar Pradesh, on Jan. 29, for 'composition of gastroretentive, buoyancy-modulated, multi-polymer microspheres of linezolid with trigger-responsive controlled release.'
Inventor(s) include Mr. Prasanjit Paul; and Mr. Nishant Gaurav.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to gastroretentive, buoyancy-modulated, multi-polymer microspheres of Linezolid designed to provide sustained and trigger-responsive oral drug delivery. The microspheres comprise a hydrophilic inner layer, a hydrophobic intermediate layer, and a pH-responsive outer layer, together forming a functional gradient matrix surrounding a hollow or low-density core that imparts prolonged gastric retention. The method of preparation includes polymer dissolution, emulsification, controlled solvent evaporation, hollow-core induction, microsphere solidification, washing, drying, and encapsulation. The resulting microspheres exhibit enhanced entrapment efficiency, reduced burst release, and controlled Linezolid release for up to 12 hours, regulated by environmental triggers such as gastric pH and hydration state."
Disclaimer: Curated by HT Syndication.
