MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202611049127 A) filed by Nims University, Jaipur, Rajasthan, on April 17, for 'compositions and methods for light-activated transdermal anesthesia in dentistry.'
Inventor(s) include Anjali Yadav.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present disclosure provides a Light-Activated Anesthetic Delivery System (LAADS) (100), comprising a novel transdermal anesthetic patch (101) for non-invasive local anesthesia in dentistry. The patch features a bio-adhesive matrix (102) containing an anesthetic reservoir (103) highly concentrated with photo-cleavable nanocarriers (104). These nanocarriers (104), such as liposomes (108), encapsulate a local anesthetic (105) and incorporate a 2-nitrobenzyl photo-cleavable linker (106). Anesthesia is achieved by placing the patch (201) and then applying an activating light (107) (e.g., 380-420 nm) for a short duration (204). The light triggers the instantaneous photolysis of the linker (106), causing a burst release (214) of the anesthetic (105) for rapid onset (207) and clinically sufficient depth. This needle-free system achieves precise duration control (208) and minimizes post-procedural numbness, addressing major limitations of current injection methods."
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