MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202541091885 A) filed by Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, on Sept. 25, 2025, for 'emulsifiable concentrate formulation of bioactive principles from xenorhabdus sp. and or photorhabdus sp and its preparation thereof.'
Inventor(s) include Dr. S. Prabhu; Dr. R. Poorniammal; Dr. N. Seenivasan; and Dr. S. Suganya Kanna.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "The present invention discloses an emulsifiable concentrate formulation of bioactive principles derived from Xenorhabdus & Photorhabdus a Gram-negative bacterium known for its potent biocontrol activity against various pests. The formulation is designed to enhance the stability, dispersibility, and increase the efficacy of the bioactive principles, allowing for easy application in agricultural and horticultural settings. The emulsifiable concentrate formulation comprises a synergistic combination of bioactive compounds extracted from Xenorhabdus & (or) Photorhabdus, including nematophin and other metabolites responsible for the insecticidal and nematicidal properties. The formulation employs a unique emulsification process, ensuring optimal mixing and dispersion of the bioactive principles in a liquid carrier, thereby enhancing their biological activity and prolonged shelf life. The preparation of the emulsifiable concentrate formulation involves a cell free multistep process. Initially, Xenorhabdus (or) Photorhabdus cultures are cultivated under controlled conditions to promote the production of bioactive metabolites. The culture broth is then subjected to various extraction techniques, such as solvent extraction or solid-phase extraction, to isolate and purify the bioactive compounds. Once purified, the bioactive compounds are carefully formulated with suitable emulsifiers, surfactants, and stabilizers to create a concentrated emulsion. The emulsification process ensures the uniform distribution of the bioactive principles throughout the formulation, preventing settling and aggregation. The resulting emulsifiable concentrate is highly stable, allowing for easy dilution and application in various pest control strategies. The disclosed emulsifiable concentrate formulation offers several advantages over conventional formulations. It exhibits improved dispersibility, enabling uniform application and enhanced coverage on plant surfaces. The formulation also provides extended residual activity, ensuring prolonged protection against target pests and nematodes. Moreover, the emulsifiable concentrate formulation is compatible with various agricultural spray equipment, making it suitable for large-scale applications . The present invention represents a significant advancement in the field of organic pest control by harnessing the power of biocontrol potential of Xenorhabdus and (or) Photorhabdus. The emulsifiable concentrate formulation offers an effective and eco-friendly solution for pest management, reducing the reliance on synthetic pesticides while providing sustainable agricultural practices. Its versatility and efficacy make it a valuable tool for farmers, researchers, and agrochemical industries seeking environmentally friendly pest control options."
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