MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202641024848 A) filed by Vignan Institute Of Pharmaceutical Technology, Visakhapatnam, Andhra Pradesh, on March 2, for 'isolation and characterization of novel alkaloids from marine sponges for antiinflammatory neuroprotection.'
Inventor(s) include G. Vasantha; M. Naga Bharathi; S. Kiranmai; R. Mohini; and D. Rama Devi.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "This invention presents a groundbreaking approach for the isolation and characterization of previously undiscovered alkaloids from marine sponges, specifically targeting their potential in providing anti-inflammatory neuroprotection. By employing a combination of bioassay-guided fractionation, advanced spectroscopic techniques, and in vitro neuronal models, the method identifies alkaloids that selectively inhibit inflammatory pathways in the brain without affecting healthy neural functions. These compounds demonstrate potent activity against neuroinflammation associated with conditions like Alzheimer's and Parkinson's diseases. The innovation lies in its eco-friendly extraction process that preserves sponge biodiversity while yielding high-purity alkaloids, validated through cellular and molecular assays showing reduced cytokine production and enhanced neuronal survival. This paves the way for developing natural-based therapeutics that offer safer alternatives to synthetic anti-inflammatory drugs, with preliminary data indicating up to 60% greater efficacy in protecting neurons from oxidative stress."
Disclaimer: Curated by HT Syndication.
