Intellectual Property India Publishes Patent Application for 'Kit Of Parts Suitable For Preparing A Biocompatible Polymeric Hydrogel' Filed by Hy2care B.V.

MUMBAI, India, Aug. 22 -- Intellectual Property India has published a patent application (202517072373 A) filed by Hy2care B.V., Geleen, Netherlands, on July 30, for 'kit of parts suitable for preparing a biocompatible polymeric hydrogel.'

Inventor(s) include Nauta, Laura; Sen, Kshama Shree; Breuer, Nick Leonardus Bianca Mathias; Both, Sanne Karijn; and Karperien, Hermanus Bernardus Johannes.

The application for the patent was published on Aug. 22, under issue no. 34/2025.

According to the abstract released by the Intellectual Property India: "The invention relates to a kit of parts suitable for preparing a biocompatible polymeric hydrogel, the kit comprising at least 2 containers each containing an aqueous composition comprising at least one of tyramine-functionalized dextran (Dex-TA), tyramine-functionalized hyaluronic acid (HA-TA), peroxidase and hydrogen peroxide, which components -when mixed- allow the formation of the biocompatible polymeric hydrogel, wherein each of peroxidase and hydrogen peroxide are present in a different container, wherein the total weight ratio of Dex-TA and HA-TA is between 75:25 and 25:75, preferably between 60:40 and 40:60, more preferably between 55:45 and 45:55; wherein the concentration of Dex-TA ranges between 2 and 7 wt% relative to the sum of aqueous compositions of the kit of parts; wherein the concentration of HA-TA ranges between 2 and 7 wt% relative to the sum of aqueous compositions of the kit of parts; wherein the DEX-TA comprises unsubstituted and TA substituted repeat units of dextran, and wherein the amount of TA substituted repeat units of DEX-TA (DSDEX) is between 5 mol% and 20 mol% relative to the total number of unsubstituted and TA substituted repeat units according to proton NMR; wherein the HA-TA comprises unsubstituted and TA substituted repeat units of hyaluronic acid, and wherein the amount of TA substituted repeat units of HA-TA (DSHA) is between 5 mol% and 20 mol % relative to the total number of unsubstituted and TA substituted repeat units according to proton NMR; wherein the DEX-TA has a weight average molecular weight (Mw) between 15 and 650 kDa; wherein the HA-TA has a weight average molecular weight (Mw) between 15 and 550 kDa; wherein the peroxidase is present in a concentration between 0.25 and 10 Units/ml and the hydrogen peroxide is present in a concentration between 0.01 and 0.10 wt%, relative to the sum of aqueous compositions of the kit of parts."

The patent application was internationally filed on Jan. 16, 2024, under International application No.PCT/EP2024/050843.

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