MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202641049329 A) filed by Sr University, Warangal, Telangana, on April 17, for 'magnetically guided intelligent nanorobots for targeted thrombus detection and therapy.'
Inventor(s) include Dr. Sarath Chandra Veerla; Dr. Babu Bathula; and Dr. Thirumala Rao Gurugubelli.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "Thrombosis, Stroke and Deep Vein Thrombosis are abnormal clotting, all of which lead to cardiovascular diseases that cause most deaths in the world. The conventional medical approaches, including anticoagulants and surgery, tend to be inaccurate and may have side effects on the whole body including profuse bleeding. A better nanotechnology-based solution is proposed in this work, and it is the application of intelligent nanorobots to identify and eliminate the clots on the surface of blood. The proposed system entails the application of biocompatible nanorobots that have magnetic nanoparticles and surface-functionalized ligands that enable them to selectively bind platelet aggregates and fibrin in clots. With the help of an external magnetic field that is controlled, these nanorobots are steered along the vascular system and the nanorobot can reach the location of the obstruction with precision. Reaching the clot, the nanorobots apply a twofold therapy: they locally administer drugs that block thrombolysis, as well as interfere with the structure of the clot on the nanoscale, thereby enhancing the effectiveness of clot dissolution. Connection to real-time image and sensors technologies would allow real-time monitoring of nanorobot location, clot size and dissolution level. Furthermore, biosensors inside it will allow taking adaptive measures, which will increase the delivery rate of drugs and minimize the damage to the surrounding healthy tissue. The system is made to be minimally invasive, which minimizes risks involved in the traditional type of surgery. This new approach has enormous advantages, as it is highly specific, systemically not toxic, therapeutic response is rapid, and patient outcomes are good. The offered nanorobotic platform can be viewed as a promising path of precision medicine, which integrates nanotechnology, robotics, and biomedical engineering to tap into the treatment of thrombotic diseases. It has the potential to become an autonomous agent in the future and be connected to AI-based diagnostics systems to realize completely automated vascular therapy. Keywords Magnetic nanorobots, Thrombus targeting, Nanomedicine, Controlled drug delivery, Biosensing systems, Minimally invasive therapy."
Disclaimer: Curated by HT Syndication.
