MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202641024849 A) filed by Vignan Institute Of Pharmaceutical Technology, Visakhapatnam, Andhra Pradesh, on March 2, for 'mechanistic insights via omics approach for synergistic interactions between plant-derived polyphenols and standard chemotherapeutics.'
Inventor(s) include D. Rama Devi; G. Vasantha; M. Naga Bharathi; S. Kiranmai; and R. Mohini.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "This invention introduces a novel omics-based methodology to uncover the underlying mechanisms of synergistic effects between plant-derived polyphenols and conventional chemotherapeutic drugs in cancer treatment. By integrating multi-omics data analysis, including genomics, transcriptomics, proteomics, and metabolomics, the approach provides comprehensive insights into how polyphenols enhance the efficacy of chemotherapeutics while reducing side effects. The method employs advanced computational tools to map molecular interactions, identify key pathways, and predict optimal combinations for personalized therapy. Unlike traditional single-target studies, this invention emphasizes holistic network analysis to reveal novel synergies, leading to improved therapeutic outcomes in various cancers. Experimental validation through in vitro and in vivo models demonstrates enhanced apoptosis, reduced drug resistance, and minimized toxicity, paving the way for safer and more effective cancer treatments."
Disclaimer: Curated by HT Syndication.
