MUMBAI, India, Sept. 12 -- Intellectual Property India has published a patent application (202421015872 A) filed by Tata Consultancy Services Limited, Maharashtra, on March 6, 2024, for 'method and system for generating tissue-wide gene expression map by super-resolving gene expression within a tissue section.'
Inventor(s) include Karambelkar, Kaushik Milind; and Baranwal, Mayank.
The application for the patent was published on Sept. 12, under issue no. 37/2025.
According to the abstract released by the Intellectual Property India: "This disclosure relates generally to a method and system for identifying gene expression map through-super-resolved histological image. State-of-art methods of gene expression profiling, such as spatial transcriptomics requires incredibly expensive experimental procedure that limits its widespread dissemination in healthcare and diagnostic sectors. The present disclosure addresses these problems through a method of identifying a tissue-wide gene expression map by performing super-resolution of gene expression in a tissue section, which contains a set of spots having a known gene expression profile. Pixels are extracted from the area surrounding the spots having the known gene expression. The machine learning model is trained on these spots to predict the gene expression on the additional spots devoid of gene expression in the entire histological image. Finally, the gene expression map is prepared by combining the spots with known gene expression and the additional spots with predicted gene expression."
Disclaimer: Curated by HT Syndication.
