MUMBAI, India, June 27 -- Intellectual Property India has published a patent application (202547058901 A) filed by Institute For Basic Science; and UNIST (Ulsan National Institute Of Science And Technology), Daejeon, Republic of Korea, on June 19, for 'method for detecting high sensitivity of cancer cell-derived extracellular vesicle gene by using fusion reaction with liposomes.'
Inventor(s) include Cho, Yoon-Kyoung; Kumar, Sumit; and Clarissa, Elizabeth Maria.
The application for the patent was published on June 27, under issue no. 26/2025.
According to the abstract released by the Intellectual Property India: "The present invention successfully introduced a new approach to target specific EV subpopulations on the basis of charge-mediated fusion of EVs and CLIPs. By adjusting the surface charge of liposomes through the ratio of positively and negatively charged lipids, the optimal ratio that allows efficient and stable fusion with exosomes was confirmed. A method according to the present invention uses the advantages of a CLIP's high fusion rate, and rapid and broad applicability, and verified excellent sensitivity and selectivity for tumor-derived EV miRNA in a lysis-free manner using droplet-microfluidics. Particularly, the EV-CLIP method enables digital detection of EGFR L858R and T790M mutations without pretreating a sample, and thus can simplify detection processes and prevent EV loss."
The patent application was internationally filed on Dec. 11, 2023, under International application No.PCT/KR2023/020308.
Disclaimer: Curated by HT Syndication.
