MUMBAI, India, July 25 -- Intellectual Property India has published a patent application (202421003607 A) filed by Intas Pharmaceuticals Ltd., Ahmedabad, Gujarat, on Jan. 18, 2024, for 'method for modulation of daratumumab glycosylation profile.'

Inventor(s) include Laxmi Adhikary; Velu Mahalingam; Viki Chopda; Dhananajay Kumar; Shreya Shah; Aadesh Dhamdhere; Swapnali Patekar; and Deeksha D Saripalla.

The application for the patent was published on July 25, under issue no. 30/2025.

According to the abstract released by the Intellectual Property India: "The present invention provides a method for modulation of galactosylation and mannosylation level of Daratumumab by supplementation of manganese chloride and modulation of afucosylation level of Daratumumab by maintaining pCO2 with pH of cell culture."

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