MUMBAI, India, May 30 -- Intellectual Property India has published a patent application (202517044770 A) filed by Amgen Inc., Thousand Oaks, U.S.A., on May 8, for 'methods of antibody characterization.'
Inventor(s) include Thomson Christy Ann; and Green Lydia Baggott.
The application for the patent was published on May 30, under issue no. 22/2025.
According to the abstract released by the Intellectual Property India: "The present disclosure relates to methods of characterizing low quantities of immunogen binding protein e.g. immunogen binding antibodies obtained directly from supernatants of individually cultured B cells. These methods which avoid hybridoma formation involve providing a preparation of B cells that secrete immunogen binding antibodies and individually culturing the B cells under conditions suitable for the B cells to secrete the immunogen binding antibodies into the culture supernatant. The culture supernatants containing the secreted antibodies are collected from the individually cultured B cells and subjected to one or more binding assays to characterize the immunogen binding antibodies (e.g. as regards their binding affinity by exposing cell culture supernatants to increasing concentrations of immunogen) from the preparation of B cells."
The patent application was internationally filed on Oct. 30, 2023, under International application No.PCT/US2023/036224.
Disclaimer: Curated by HT Syndication.
