MUMBAI, India, June 20 -- Intellectual Property India has published a patent application (202517048923 A) filed by Neurosterix Pharma Sarl, Geneva, on May 21, for 'novel pyrrolo[1,2-d][1,2,4]triazin-1-one derivatives as negative allosteric modulators of mglu7 receptors.'
Inventor(s) include Paparin, Jean-Laurent; Rocher, Jean-Philippe; Rutjes, Floris, Petrus, Johannes, Theodorus; Janssen, Freek, Jan; Derks, Max, Theodorus, Gerardus, Maria; Lacour, Antoine, Michel, Lauder; and Van Der Kolk, Marnix, Ruben.
The application for the patent was published on June 20, under issue no. 25/2025.
According to the abstract released by the Intellectual Property India: "The present application relates to compounds of Formula (I), wherein P, Q, A, B, m, n, R1, R3 and R are defined as in Formula (I) which are negative allosteric modulators of the metabotropic glutamate receptor subtype 7 (mGlu7) and which are useful for the treatment or prevention of neurological, ear and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGlu7 subtype of metabotropic receptors is involved. The application is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and such compositions, and to the use of such compounds for the prevention or treatment of neurological, ear and psychiatric disorders and diseases in which mGlu7 is involved."
The patent application was internationally filed on Nov. 14, 2023, under International application No.PCT/EP2023/081732.
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