MUMBAI, India, Aug. 1 -- Intellectual Property India has published a patent application (202411003754 A) filed by ITC Limited, New Delhi, on Jan. 19, 2024, for 'permeation enhancement matrix composition.'
Inventor(s) include Rohith Kumar Agarthimoole; Prabakaran Ravichandran; Sabarinathan Devan; Maheswaran Sivasamban Karatholuvhu; Yashwanth Radhakrishnan; Soumitra Mukherjee; and Suresh Ramamurthi.
The application for the patent was published on Aug. 1, under issue no. 31/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to a prosome composition and a method for its preparation. The composition comprises a naturally or synthetically derived active ingredient, a lipid matrix, a non-aqueous solvent, and excipients, forming free-flowing granules capable of liposome formation upon hydration. The lipid matrix includes saturated and unsaturated fatty acids, or their esters and the active ingredient constitutes up to 75% by weight. The preparation involves a non-aqueous slurry and rotary evaporation at mild to moderate temperatures of (25-55 C), ensuring stability of temperature-sensitive actives. This scalable process enhances the permeability of actives through buccal route, offering advantages over traditional lyophilization and dehydration techniques. Applications include edible formats like pouches, gums, tablets, and non-edible forms such as patches, enabling efficient delivery of bioactive in pharmaceutical, nutraceutical, and consumer health products."
Disclaimer: Curated by HT Syndication.