MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202611009622 A) filed by Indian Council Of Agricultural Research, New Delhi, on Jan. 30, for 'process of extraction of high molecular weight bioactive lentinan from mushrooms.'
Inventor(s) include Veda Krishnan; C S Keerthana; Shuvarghya Chakraborty; Muskan Beura; Susheel Kumar Sharma; Archana Singh; and Anil Dahuja.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a method for the extraction, purification, and quantification of high molecular weight LNT from Lentinula edodes, ensuring preservation of its bioactive triple-helical structure. The methodology involves pulverization, sieving, acidalkali-assisted extraction, filtration, dialysis, gel permeation chromatography, and lyophilization, followed by colorimetric assays to quantify total and high molecular weight B-glucans. The structural integrity was validated using FTIR compared to commercial reference, and inhibitory potential towards starch digestion (i.e., hypoglycemic effect) was validated in dose dose-dependent manner using starch hydrolyzation kinetics. This novel procedure will enable elucidation of its molecular mechanisms and development of functional foods or nutraceuticals that leverage its bioactivity. Additionally, optimizing the extraction method for large-scale production and assessing the stability and bioavailability of THG in processed food products will be essential to harness its therapeutic potential for diabetes management and clinical applications."
Disclaimer: Curated by HT Syndication.
