MUMBAI, India, Jan. 23 -- Intellectual Property India has published a patent application (202541116154 A) filed by Psg Institute Of Medical Sciences & Research; Psg College Of Arts And Science; and Psg Institute Of Technology And Applied Research, Coimbatore, Tamil Nadu, on Nov. 24, 2025, for 'production of vanillin and guaiacol based trifunctional glycidylmethacrylate dental hybrid composite.'
Inventor(s) include M. Selvi; S. Devaraju; E. Satheesh Kumar; T. M. Subbarao; and M. Alagar.
The application for the patent was published on Jan. 23, under issue no. 04/2026.
According to the abstract released by the Intellectual Property India: "The present invention deals with the production and characterization of biobased non-estrogenic dental restorative hybrid composites using modified vanillin and guaiacol based trifunctional glycidylmethacrylate (VG-trisGMA) with bio-compatible and non-toxic reinforcements/fillers (bio-silica, hydroxyapatite, and yttria-stabilized zirconia (YSZ)), triethylene glycol bismethacrylate (TEGDMA) as a diluent, along with combination of photoinitiators [(camphorquinone (CQ) and ethyl-4-dimethylaminobenzoate (EDAB)]. The properties ofYG- tris-GMA matrices and its hybrid composites are studied using appropriate analytical instruments and standard methods with a view to ascertain their suitability for dental restorative and denture applications. The weight percentage ratio of photo-initiators system required to cure VG- tris-GMA is in the range of 0.5-1.5 wt%. The depth of the cured composite exceeds 3 mm under standard conditions. the curing of YG- trisGMA is achieved by visible-light irradiation for 60 seconds in the absence of TEGDMA as a diluent. The curing time of the hybrid matrix comprising VGtris- GMA and TEGDMA (I: I w/w) in the presence of CQ and EDAB photoinitiators is found to be 70-80 seconds. The curing time of the hybrid composites comprising ofYG-tris-GMA/TEGDMA (I: I w/w) in the presence ofCQ and EDAB photo-initiators along with fillers are found to be in the range between 65 and 80 seconds with the thickness of about 7 mm. The value of water contact angle of YG- tris-GMA and fillers reinforced VG- tris-GMA composites are ranged between 115 and 128. Similarly, the values of percentage of moisture absorption of reinforced YG-GMA composites are ranged between 2.5% and 4.5%. The solubility of VG-tris-GMA/TEGDMA hybrid composites immersed in artificial saliva for 7 days at ambient temperature is found to be less than 4.5 wt%. The viscosity ofVG- tris-GMA varies within 5% variation over a storage period of 60 days at 25 C in lightprotected packaging. The compressive strength of cured VG- tris-GMA and its hybrid composites were found in lhe range between 50 MPa and 75 MPa. The hardness shoreD of cured VG- tris-GMA and its hybrid composites were found in the range between 40 and 68. The cyto-toxic behavior of the VG- trisGMA showing 85% cell viability when tested in-vitro cyto-toxicity-MIT method cell line L929 confirming suitability for biomedical application. The present invention considered as cutting-edge concept in the field of utilization of bio-material for dental restoration and denture applications."
Disclaimer: Curated by HT Syndication.
