MUMBAI, India, June 20 -- Intellectual Property India has published a patent application (202517023417 A) filed by Affinia Therapeutics Inc., Waltham, U.S.A., on March 17, for 'recombinant aavs with improved tropism and specificity.'

Inventor(s) include Albright, Charles Francis; Olivieri, Kevin C; Cao, Xiaohong; and Tan, Jie.

The application for the patent was published on June 20, under issue no. 25/2025.

According to the abstract released by the Intellectual Property India: "The present disclosure provides a modified AAV capsid protein comprising a targeting peptide in variable region VIII (VR. VIII) and/or a peptide segment in variable region I (VR I). The modified AAV capsid protein can form an rAAV, which has a preferred tropism, specificity or biodistribution in vivo or in vitro. The rAAV of the present disclosure can be used for gene therapies targeted at a specific tissue."

The patent application was internationally filed on Aug. 17, 2023, under International application No.PCT/US2023/072424.

Disclaimer: Curated by HT Syndication.