MUMBAI, India, July 25 -- Intellectual Property India has published a patent application (202411002195 A) filed by Amity University, Noida, Uttar Pradesh, on Jan. 11, 2024, for 'self-emulsifying drug delivery system for enhanced antimalarial therapy and method thereof.'
Inventor(s) include Richa Srivastava; Zeeshan Fatima; Prashant Shukla; and Jagannath Sahoo.
The application for the patent was published on July 25, under issue no. 30/2025.
According to the abstract released by the Intellectual Property India: "The present invention discloses pharmaceutical composition and a self-emulsifying drug delivery system for enhanced antimalarial therapy and method thereof. The present invention elucidates a novel self-emulsifying drug delivery system that combines DHA and quercetin. This system significantly improves the solubility and bioavailability of these compounds, leading to enhanced therapeutic efficacy against multidrug-resistant Plasmodium strains. we have prepared self-emulsifying drug delivery system of dihydroartemesinin along with quercetin which has shown good antimalarial activity against Plasmodium yoelii MDR (Multidrug Resistant) in Swiss mice. The formulation prepared using drug showed cure rate of 100%, at a dose of 120 mg/kg (20 mg/kg DHA and 100 mg/kg quercetin). The excipients used in preparing formulation were found to aid the therapeutic effect of the formulation."
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