MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202611025663 A) filed by Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, on March 4, for 'smart biomaterial-based closed-loop drug delivery device with multi-parameter saturation sensing and adaptive release modulation.'
Inventor(s) include Sachin Kumar; and Dr. Lubhan Singh.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a smart biomaterial-based closed-loop drug delivery device configured to autonomously regulate therapeutic release in response to localized physiological saturation at a target tissue site. The device comprises a drug reservoir, a multi-parameter physiological sensing module, a processor with a saturation computation unit, and a release modulation unit incorporating a stimuli-responsive biomaterial matrix. The sensing module detects parameters including drug concentration gradients, receptor occupancy levels, tissue impedance variation, microenvironmental pH shifts, enzymatic activity, or metabolic turnover rates. A Local Saturation Index (LSI) is computed using weighted combinations of the detected parameters and compared with predefined thresholds. Based on the LSI, the release modulation unit dynamically alters permeability, pore geometry, or diffusion characteristics of the biomaterial matrix to proportionally regulate therapeutic output. The biomaterial matrix may comprise chitosan-based hydrogels, polyethylene glycol (PEG)-crosslinked polymers, polylactic-co-glycolic acid (PLGA), alginate composites, or ligand-functionalized networks."
Disclaimer: Curated by HT Syndication.
