MUMBAI, India, Aug. 29 -- Intellectual Property India has published a patent application (202517074507 A) filed by Cerevel Therapeutics, Llc, Chicago, on Aug. 5, for 'spiro derivatives as m4 activators/modulators and uses thereof.'

Inventor(s) include Nguyen, Hanh; Zhang, Xiaofeng; Johnson, Shea; Zhang, Hongjun; Lim, Jongwon; Pin, Sokhom; Sarkar, Ujjal; Wang, Minghua; and Gray, David.

The application for the patent was published on Aug. 29, under issue no. 35/2025.

According to the abstract released by the Intellectual Property India: "The present disclosure provides compounds of Formula I: (l) (I), or an N- oxide thereof, or a pharmaceutically acceptable salt of the compound or the N-oxide, wherein: A, Y, m, n,p, R1, R2, R3, R3a, R4, R5, R6, R7, and Z are as described herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds, N-oxides, or salts, and their uses for treating M4-mediated (or M4-associated) disorders including, e.g., Alzheimer's Disease, Parkinson's Disease, schizophrenia (e.g., its cognitive and negative symptoms), pain, addiction, and a sleep disorder."

The patent application was internationally filed on Jan. 11, 2024, under International application No.PCT/US2024/011203.

Disclaimer: Curated by HT Syndication.