MUMBAI, India, Jan. 23 -- Intellectual Property India has published a patent application (202521124993 A) filed by Dr. D. Y. Patil Institute Of Pharmaceutical Sciences And Research; School Of Pharmacy And Research; and Dr. Rakesh Mishra, Pune, Maharashtra, on Dec. 11, 2025, for 'synergistic transdermal delivery of hydrophilic and lipophilic drugs using microneedles and transferosomal vesicles.'
Inventor(s) include Dr. Rakesh Mishra; Dr. Abhishek Jha; Ms. Neha Pandit; and Ms. Radhika Baheti.
The application for the patent was published on Jan. 23, under issue no. 04/2026.
According to the abstract released by the Intellectual Property India: "The invention introduces a cutting-edge transdermal delivery system that merges microneedle arrays with transferosomal vesicles to co-administer hydrophilic and lipophilic drugs. Initially, micron-scale needles discreetly puncture the stratum corneum to create microchannels. Subsequently, innovative ultradeformable transferosomes, carrying both a water-soluble drug (e.g. gallic acid) and a lipid-soluble drug (e.g. rutin), are applied. These transferosomes adapt and navigate through the microneedle-generated pores to penetrate deeper skin layers, effectively dispensing the drugs for enhanced absorption. This collaborative approach effectively overcomes the individual limitations of each technique, notably increasing dermal permeability and systemic bioavailability of the active ingredients. This sophisticated system is perfectly suited for pharmaceutical patches or gels, offering a minimally invasive and regulated mode for administering combination therapies. The invention is particularly applicable in transdermal therapy and skincare products requiring dual-mode drug delivery."
Disclaimer: Curated by HT Syndication.
