MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202641024822 A) filed by Vignan Institute Of Pharmaceutical Technology, Visakhapatnam, Andhra Pradesh, on March 2, for 'thermosensitive liposomal carriers with magnetic nanoparticles for hyperthermiatriggered chemotherapy.'
Inventor(s) include M. Saritha; P. V. Kamala Kumari; P. N. Mallikarjun; S. Satya Lakshmi; U. Bhavani; and K. Srilekhya.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "This invention introduces a novel system of thermosensitive liposomal carriers embedded with magnetic nanoparticles designed specifically for hyperthermia-triggered chemotherapy. The carriers are engineered to encapsulate chemotherapeutic drugs and respond to mild heat generated by an external alternating magnetic field, enabling precise drug release at tumor sites. By combining magnetic targeting, heat-induced liposomal destabilization, and controlled drug delivery, the system aims to enhance the efficacy of cancer treatment while minimizing side effects on healthy tissues. Key features include superparamagnetic iron oxide nanoparticles for heat mediation, thermosensitive lipids that phase-transition at around 40-45 C for rapid drug release, and surface modifications for improved circulation and tumor accumulation. Preclinical evaluations demonstrate synergistic effects between hyperthermia and chemotherapy, leading to increased tumor cell apoptosis, better drug penetration, and reduced systemic toxicity compared to conventional methods."
Disclaimer: Curated by HT Syndication.
