MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202641025606 A) filed by Dr. Yesudasu Vasimalla; Dr. Santosh Kumar; and Koneru Lakshmaiah Education Foundation, Vaddeswaram, Andhra Pradesh, on March 4, for 'ultra-sensitive long range spr biosensor enhanced with ag/zno/pda/graphene co-modification for detecting igg.'

Inventor(s) include Pedapati Jayanth Venkata Sai Sricharan; Sandeep Boddu; Dr. Yesudasu Vasimalla; and Dr. Santosh Kumar.

The application for the patent was published on March 13, under issue no. 11/2026.

According to the abstract released by the Intellectual Property India: "A proposal of an ultra-sensitive multilayer surface plasmon resonance (SPR) biosensor using a ZnO/Ag/PDA/Graphene platform is proposed and numerically characterized to detect immunoglobulin G (IgG). Angular interrogation of the structure with a wavelength of 633 nm is done using the Transfer Matrix Method (TMM) to analyse the optical performance of the structure. The optimization analysis demonstrates that the 60 nm layer of Ag gives a better sharpness of resonance and a high plasmon coupling efficiency. The relative study of three configurations shows that addition of ZnO, PDA, and graphene improves resonance angle shift and sensitivity remarkably. Additional optimization suggests that 20 nm PDA layer is optimized to reach a maximum angular sensitivity of 237.04 /RIU, and the quality factor and signal-noise ratio is enhanced. The suggested structure has excellent performance over various conventional and prism-based SPR sensors that are 2D material-assisted. The proposed multilayer SPR biosensor is based on ZnO/Ag/PDA/Graphene has a high sensitivity, sharp resonance properties, and high index of refraction, and has a high potential in real-time, label-free, and high-resolution IgG diagnostics due to its sensitiveness and high responsiveness in biomedical and clinical uses."

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