Intellectual Property India Publishes Patent Application for 2-Azetidinyl-7-Methyl-8-Oxo-6-(trifluoromethyl)-7,8-Dihydropyrimido[5,4-D]pyrimidine Derivatives Derivatives As Trem2 Modulators For The Treatment Of Neurodegenerative Diseases

MUMBAI, India, Aug. 10 -- Intellectual Property India has published a patent application (202617075084 A) filed by Muna Therapeutics Aps on June 17, 2026, for 2-Azetidinyl-7-Methyl-8-Oxo-6-(trifluoromethyl)-7,8-Dihydropyrimido[5,4-D]pyrimidine Derivatives Derivatives As Trem2 Modulators For The Treatment Of Neurodegenerative Diseases.

Inventors include Busch-Petersen, Jakob; and Whitlock, Gavin.

The application for the patent was published on July 31, 2026, under issue no. 31/2026.

Abstract: The present invention relates to compounds of formula (I) useful for modulating Triggering Receptor Expressed on Myeloid Cells-2 ("TREM2"). The invention also relates to the compounds for use in treatment of conditions related to loss of function of TREM2, such as e.g. neurodegenerative diseases, and to pharmaceutical compositions comprising the compounds.

Disclaimer: Curated by HT Syndication.