MUMBAI, India, July 7 -- Intellectual Property India has published a patent application (202511104342 A) filed by Indian Institute Of Technology Banaras Hindu University, Varanasi on October 29, 2025, for A 3d Hydrogel-Based Formulation And A Method Of Synthesis Thereof.
Inventors include Sudip Mukherjee; Sumit Manna; Pragya Pallavi; and Lipi Pradhan.
The application for the patent was published on July 03, 2026, under issue no. 27/2026.
Abstract: The present invention provides a 3D bioprintable, biocompatible and stable hydrogel-based formulation that facilitates sustained release of therapeutic molecules for the management of neurodegeneration. The hydrogel-based formulation comprises of an engineered cell as a bioactive material that includes a mammalian cell transfected with a vector encoding a gene of a biomolecule, a selection marker and a promoter sequence, encapsulated in a hydrogel scaffold fabricated with a polymeric ink that releases the biomolecule, thus ensuring the prolonged survival and ensuring delivery of the biomolecule through the blood-brain-barrier. Therefore, the present invention provides a construct with desirable geometry that allows diffusion of nutrients and facilitates blood vessel growth that support the viability of the engineered cells, thus providing efficient management of neurodegeneration. Figure 1 on sheet no. 1 of the drawings may accompany the abstract when published.
Disclaimer: Curated by HT Syndication.
