MUMBAI, India, July 24 -- Intellectual Property India has published a patent application (202441074314 A) filed by Manipal Academy Of Higher Education on April 01, 2025, for A Composition And Method For Sustained-Release Dry Powder Inhaler Using A Polymeric Particulate Matrix.
Inventors include A Supraja; Muddukrishna Bs; Girish Pai K; Virendra S Ligade; K Sreedhara Ranganath Pai; Vasantharaju Sg; Gundawar Ravi; and Namadev L. Dhash.
The application for the patent was published on July 17, 2026, under issue no. 29/2026.
Abstract: A COMPOSITION AND METHOD FOR SUSTAINED-RELEASE DRY POWDER INHALER USING A POLYMERIC PARTICULATE MATRIX The invention discloses a sustained-release dry powder inhalation formulation developed for pulmonary delivery of a bronchodilator for management of chronic obstructive pulmonary disease. The invention provides a particulate-based inhalation system configured to achieve controlled drug release, improve formulation performance, and enhance suitability for capsule-based dry powder inhaler administration. The formulation is prepared through a controlled particle-engineering process followed by drying, powder blending, and inhalation dosage-form preparation. The invention further includes optimization of formulation and process variables to obtain desirable particle characteristics, drug entrapment, loading efficiency, powder flow, solubility enhancement, and in-vitro release behavior. By integrating controlled-release formulation design with inhalation-compatible powder processing, the invention provides an improved pulmonary drug-delivery platform intended to reduce repeated dosing burden and support better therapeutic performance in long-term respiratory treatment. FIG.2
Disclaimer: Curated by HT Syndication.
