MUMBAI, India, Aug. 12 -- Intellectual Property India has published a patent application (202421079997 A) filed by Indian Institute Of Science Education And Research, Pune Iiser Pune on October 21, 2024, for A Continuous-Flow Catalytic Dehydration Process For The Synthesis Of Macrocyclic Compounds.
Inventors include Gnanaprakasam, Boopathy; Sutar, Dashrat Vishambar; and Jamdade, Akash Bandu.
The application for the patent was published on August 07, 2026, under issue no. 32/2026.
Abstract: The present invention relates to a continuous-flow catalytic dehydration process for the synthesis of macrocyclic compounds. More specifically, the present invention relates to a process of synthesizing macrocyclic ether, macrolactone and macrolactam compouds of formula (I) in good yields and also demonstrated in gram scale application. Further, the process of the present invention of synthesizing new macrocyclic compounds generates only water as a by-product. The advantages of the process of present invention include heterogeneous catalysis and scalable to grams, diverse substrates with different ring sizes, water as a by-product, no requirement of predefined substrates, and no special reaction conditions.
Disclaimer: Curated by HT Syndication.
