MUMBAI, India, Aug. 10 -- Intellectual Property India has published a patent application (202441056992 A) filed by Ismo Bio-Photonics Pvt. Ltd.; and Ikram Khan. S. I on January 26, 2025, for A Handheld Microspheroid Generator And Dispenser.
Inventor includes Ikram Khan. S. I.
The application for the patent was published on July 31, 2026, under issue no. 31/2026.
Abstract: The present invention relates to a compact, automated handheld device (10) for accurate generation, enumeration, and high-speed dispensing of microspheroids with homogeneous size control. The device features a microfluidic architecture comprising multiple on-chip vials (19) or cascaded chip configured for simultaneous, sequential, or on-demand generation of heterogeneous microspheroids form different cell types. An integrated optical sensor-based imaging system comprising a CMOS camera (8) and imaging lens (7) enables real-time visualization and quantification of the generated microspheroids prior to dispensing. A microcontroller-based control system (9) regulates fluid flow parameters to ensure precise size control, accurate counting, and automated dispensing. The microfluidic system delivers spheroid culture suspensions with controlled dimensions onto different target membranes or materials for applications including drug screening. The device is further adaptable for generation and dispensing of induced pluripotent stem cell (iPSC)-derived organoids or induced organoids for heterogeneous tissue modeling and research purposes. Fig. 1
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