MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202641084102 A) filed by Vellore Institute Of Technology on July 08, 2026, for A Method For Preparing A Boronic Acid Functionalized Graphene Oxide-Chitosan Hybrid Film.
Inventors include A. Joseph Nathanael; R. Divya; and Dr. Sushma Kumari.
The application for the patent was published on July 10, 2026, under issue no. 28/2026.
Abstract: The present disclosure proposes a method for preparing a boronic acid functionalized graphene oxide-chitosan hybrid film exhibiting enhanced bacterial capture, antibacterial activity, biofilm inhibition, substrate adhesion, mechanical stability, and multi-surface coating performance through synergistic integration of functionalized graphene oxide within a chitosan matrix. The method comprises covalently functionalizing graphene oxide with 4-aminophenylboronic acid to obtain APBA-modified graphene oxide (AGO) bearing boronic acid functional groups, incorporating the AGO into a chitosan solution to form a hybrid nanocomposite composition, and applying it onto a substrate to form a self-adhesive antibacterial film. The boronic acid functional groups form reversible covalent bonds with cis-diol-containing bacterial surface biomolecules, facilitating bacterial capture, while graphene oxide induces membrane disruption and oxidative stress, and chitosan provides contact-killing activity. The hybrid film exhibits substrate-independent adhesion on glass, metal, plastic, and titanium, with enhanced mechanical strength, thermal stability, reduced swelling, and potent antibacterial and anti-biofilm efficacy against E. coli and S. aureus.
Disclaimer: Curated by HT Syndication.
