MUMBAI, India, Aug. 10 -- Intellectual Property India has published a patent application (202411104309 A) filed by Lingaya'S Vidyapeeth on December 30, 2024, for A Method For Synthesis Of Heterocyclic Derivatives Of Phthalic Anhydride With Substituted Amines.
Inventors include Mr. Bhavik Kuchipudi; Mr. Viraj Gadde; Dr. Radhe Shyam; Dr. Konica Sharma; Dr. Rizwan Arif; Dr. Ajay Pal Singh; Dr. Mamta Bishnoi; Dr. Javalkar Dinesh Kumar; Dr. Manoj K Malik; Ar. Aditi Arora; Dr. Mortha Chinna Rao; Dr Prasad Dharnasi; Dr P Sudheer; Mr. Arshdeep Chopra; and Mr. Saurabh Kumar.
The application for the patent was published on July 31, 2026, under issue no. 31/2026.
Abstract: ABSTRACT A METHOD FOR SYNTHESIS OF HETEROCYCLIC DERIVATIVES OF PHTHALIC ANHYDRIDE WITH SUBSTITUTED AMINES A method (100) for synthesis of heterocyclic derivatives of phthalic anhydride with substituted amines. Further, the method comprisingreacting phthalic anhydride with substituted amines selected from the group consisting of 2,4-dinitrophenyl hydrazine, p-nitro amine, and o-phenylenediamine in a condensation reaction. Further, monitoring the progress of the reaction using Thin Layer Chromatography (TLC) in a solvent system of ethyl acetate and hexane in a 1:1 molar ratio. Further, isolating and purifying the synthesized heterocyclic derivatives. Further, characterizing synthesized heterocyclic derivatives by infrared (IR) spectroscopy, Ultraviolet-Visible (UV-Visible) spectroscopy. Nuclear Magnetic Resonance (NMR) spectroscopy. Further, comprising studying the antioxidant properties of the synthesized heterocyclic derivatives using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical assay FIG. 1
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