MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202621107091 A) filed by Dr. Khan Ayesha Tazeen; Patil Jayant Vijaykumar; Shaikh Mohammad Altamash Mujib; Shaikh Mohammed Kaif Arefullha; Rohit Krishna Katare; Kalyani Sunil Edhate; Geetanjali Sanjay Ambhore; Apurva Satish Thole; Vaishnavi Ganesh Daud; Om Laxman Thakare; Pallavi Narayan Kangare; and Swapnil S Kulkarni on September 05, 2026, for A Multifunctional Hydrogel–nanoparticle Composite Wound Dressing With Controlled Antimicrobial Drug Release And Accelerated Tissue Regeneration Capability.
Inventors include Dr. Khan Ayesha Tazeen; Patil Jayant Vijaykumar; Shaikh Mohammad Altamash Mujib; Shaikh Mohammed Kaif Arefullha; Rohit Krishna Katare; Kalyani Sunil Edhate; Geetanjali Sanjay Ambhore; Apurva Satish Thole; Vaishnavi Ganesh Daud; Om Laxman Thakare; Pallavi Narayan Kangare; and Swapnil S Kulkarni.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: [052] The present invention provides a multifunctional hydrogel–nanoparticle composite wound dressing integrating infection-responsive antimicrobial delivery with tissue-regenerative support. The dressing comprises a biocompatible hydrogel matrix having a structural network and an adaptive release-controlling network, functional nanoparticles carrying an antimicrobial therapeutic agent, and a tissue-contacting bioactive region. The antimicrobial agent is controlled by a nanoparticle- level retention barrier and a hydrogel-level transport barrier, while at least one hydrogel, particle, coating or drug interaction responds to a wound-associated stimulus including pH, reactive oxygen species, enzyme activity, ionic strength or exudate content. The responsive interaction modifies antimicrobial flux without requiring an external electronic controller, while the structural network maintains dressing integrity. The hydrated matrix manages exudate and moisture, and the bioactive region supports cell migration, extracellular-matrix formation and regenerative processes. The invention further provides methods for preparing and using the composite so that elevated wound-associated signals can increase antimicrobial availability and subsequent wound stabilisation can reduce unnecessary antimicrobial flux while regenerative support is maintained. Accompanied Drawing [FIGS. 1-2].
Disclaimer: Curated by HT Syndication.
