Intellectual Property India Publishes Patent Application for A Process For The Preparation Of Veterinary Topical Pharmaceutical Composition Comprising Zinc Oxide Nanoparticles For Ovine Foot Rot

MUMBAI, India, Oct. 12 -- Intellectual Property India has published a patent application (202611103249 A) filed by Dr. Amatul Muhee; Dr. Ubaid Farooq; Dr. Md. Isfaqul Hussain; Dr. Mohammad Iqbal Yatoo; Dr. Mohsin Ayoub Mire; Dr. Tariq Maqbool; Dr. Maliha Gulzar; and Dr. Rather Izhar Ul Haq on August 27, 2026, for A Process For The Preparation Of Veterinary Topical Pharmaceutical Composition Comprising Zinc Oxide Nanoparticles For Ovine Foot Rot.

Inventors include Dr. Amatul Muhee; Dr. Ubaid Farooq; Dr. Md. Isfaqul Hussain; Dr. Mohammad Iqbal Yatoo; Dr. Mohsin Ayoub Mire; Dr. Tariq Maqbool; Dr. Maliha Gulzar; and Dr. Rather Izhar Ul Haq.

The application for the patent was published on October 09, 2026, under issue no. 41/2026.

Abstract: Abstract A Process for the Preparation of Veterinary Topical Pharmaceutical Composition Comprising Zinc Oxide Nanoparticles for Ovine Foot Rot A veterinary topical pharmaceutical composition for the management of ovine foot rot caused by Dichelobacter nodosus is disclosed, comprising zinc oxide nanoparticles (particle size 100 nm) homogeneously dispersed in a petroleum-jelly-based semisolid carrier vehicle at a concentration of about 2000 µg/mL, together with a process for its preparation comprising heating and liquefying petroleum jelly, incorporating a zinc oxide nanoparticle stock suspension under continuous stirring, and cooling to obtain the composition in paste form. The composition exhibits antimicrobial activity against D. nodosus over a concentration range of about 1000 µg/mL to about 8000 µg/mL, benchmarked against standard antibiotic discs of enrofloxacin and oxytetracycline, and acceptable in vitro cytocompatibility on L929 fibroblasts. In naturally infected sheep, the composition produced a significantly lower lameness score, lower rectal temperature and respiratory rate, and a significantly reduced mean time to complete clinical recovery, relative to conventional antibiotic therapy, thereby providing an antibiotic-sparing topical option for managing ovine foot rot.

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