MUMBAI, India, Aug. 12 -- Intellectual Property India has published a patent application (202611070211 A) filed by Ims Engineering College, Ghaziabad on June 04, 2026, for An Ai-Assisted Crispr-Based Gene Editing Optimization System And Method For Precision Genome Engineering.

Inventors include Dr. Shomini Parashar; Miss Vandna Tomar; Dr. Mohit Arya; and Dr. Sandeep Kumar.

The application for the patent was published on August 07, 2026, under issue no. 32/2026.

Abstract: The present invention discloses an AI-assisted CRISPR-based gene editing optimization system and method for precision genome engineering and adaptive genetic modification applications. The invention integrates genomic data acquisition modules, artificial intelligence prediction engines, machine learning frameworks, automated guide RNA optimization systems, adaptive CRISPR editing controllers, cloud-based computational infrastructure, and real-time sequencing feedback mechanisms to improve editing accuracy, efficiency, and biological safety. The system intelligently identifies optimal genomic target regions, minimizes off-target mutations, dynamically optimizes editing parameters, and continuously refines editing strategies using reinforcement learning algorithms and predictive genomic analytics. The disclosed invention supports multiple CRISPR-associated proteins including Cas9, Cas12, Cas13, prime editors, and base editors, while additionally enabling adaptive delivery mechanism selection and repair pathway optimization. The invention is applicable in therapeutic gene correction, personalized medicine, cancer treatment, agricultural biotechnology, synthetic biology, pharmaceutical development, and industrial microorganism engineering. The disclosed system significantly enhances genome editing precision, scalability, automation, and reliability compared to conventional CRISPR-based technologies. Accompanied Drawing [FIGS. 1-2]

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