MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202617073748 A) filed by Neurimmune AG; and Alexion Pharmaceuticals, Inc. on June 14, 2026, for Anti-Transthyretin Antibody, Compositions Comprising Said Antibody And Methods For Treating Or Preventing Transthyretin-Mediated Amyloidosis.
Inventors include Michalon, Aubin; Salzmann, Michael; Godawat, Rahul Number; and Sui, Siguang.
The application for the patent was published on July 10, 2026, under issue no. 28/2026.
Abstract: Provided herein are anti-transthyretin (TTR) antibodies, corresponding polynucleotides and expression vectors as well as compositions (e.g., pharmaceutical compositions) and related articles of manufacture that contain the anti-TTR antibody as a drug. Provided herein are also methods of treating or preventing transthyretin-mediated amyloidosis (ATTR) in a subject in need thereof using the pharmaceutical compositions. Additionally, provided herein are methods for validating, identifying, and screening of an amyloid depleting drug using high-resolution live-cell imaging as well as methods for producing a pharmaceutical composition of an amyloid depleting drug and kits suitable for use in said methods.
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