MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202617090138 A) filed by Obsidian Therapeutics, Inc. on July 24, 2026, for Compositions And Methods For Tunable Regulation Of Il15 And Light.
Inventors include Passaro, Carmela; Sethi, Dhruv; Ter Meulen, Jan; and Ols, Michelle.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: Provided herein are nucleic acid molecules comprising a first nucleic acid encoding a polypeptide payload operably linked to a first drug responsive domain (DRD) and a second nucleic acid encoding a LIGHT polypeptide operably linked to a second DRD. The abundance, availability, and/or biological activity of the polypeptide payload and the LIGHT polypeptide is regulated by interaction of an effective amount of the first and second nucleic acid with an effective amount of at least one ligand. Vectors and cells comprising the nucleic molecules provided herein are provided, as are methods of making and using the nucleic molecules.
Disclaimer: Curated by HT Syndication.
