Intellectual Property India Publishes Patent Application for Crystalline Polymorphic Forms Of Marimastat, An Amorphous Form Of Marimastat, Processes For Their Preparation, Pharmaceutical Compositions Comprising The Same, And Uses Thereof

MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202617089954 A) filed by Pikralida Splka Z Ograniczona Odpowiedzialnoscia; and Instytut Biologii Doswiadczalnej Im. Marcelego on July 24, 2026, for Crystalline Polymorphic Forms Of Marimastat, An Amorphous Form Of Marimastat, Processes For Their Preparation, Pharmaceutical Compositions Comprising The Same, And Uses Thereof.

Inventors include Masnyk, Marek; Sidoryk, Katarzyna; Mucha, Lukasz; Magdycz, Marta; Tyszkiewicz, Magdalena; and Pikul, Stanislaw.

The application for the patent was published on October 23, 2026, under issue no. 43/2026.

Abstract: The invention relates to a crystalline polymorphic form I, II and III of marimastat, a mixture of the crystalline polymorphic form I and III of marimastat, an amorphous form of marimastat, and processes for their preparation. The invention further relates to a pharmaceutical composition comprising the crystalline polymorphic form I, II or III of marimastat, the mixture of the crystalline polymorphic form I and III of marimastat, the amorphous form of marimastat or a mixture thereof. The invention also relates to the pharmaceutical composition, the crystalline polymorphic form I, II or III of marimastat, the mixture of the crystalline polymorphic form I and III of marimastat, the amorphous form of marimastat or a mixture thereof for use as a medicament, and for use in the prevention and treatment of diseases associated with hyperactivity of extracellular matrix metalloproteinases.

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