MUMBAI, India, June 22 -- Intellectual Property India has published a patent application (202641070024 A) filed by Brahmaiah Bonthagarala; Dr. Kameswara Rao Sankula; Dr. Sushma. N; Dr. Sailaja Gunnam; Abhisake Maji; Ujjal Manna; Vinjavarapu L Anusha; and Dr Y Ratna Sindhu on June 04, 2026, for Development And Characterization Of A Novel Herbal Anti-Inflammatory Cream For Topical Application.
Inventors include Brahmaiah Bonthagarala; Dr. Kameswara Rao Sankula; Dr. Sushma. N; Dr. Sailaja Gunnam; Abhisake Maji; Ujjal Manna; Vinjavarapu L Anusha; and Dr Y Ratna Sindhu.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: The present invention relates to the development and characterization of a novel herbal anti-inflammatory cream intended for topical application. The formulation is designed using natural plant extracts with proven anti-inflammatory, antimicrobial, and skin-soothing properties. The herbal ingredients incorporated in the formulation include extracts of Curcuma longa, Azadirachta indica, Aloe barbadensis Miller, essential oil of Mentha piperita, and aromatic oil obtained from Rosa damascena. These herbal components are combined with suitable pharmaceutical excipients such as beeswax, liquid paraffin, borax, methyl paraben, and distilled water to produce a stable topical cream formulation. The prepared cream is formulated using a conventional emulsification method in which the oil phase and aqueous phase are separately prepared and subsequently mixed to obtain a homogeneous semi-solid preparation. The formulation is evaluated for various physicochemical parameters including appearance, pH, spreadability, viscosity, homogeneity, washability, and stability. The results indicate that the developed herbal cream exhibits acceptable physicochemical properties, good stability, and compatibility with skin pH. The combination of selected herbal extracts provides synergistic anti-inflammatory, antimicrobial, moisturizing, and soothing effects. Therefore, the developed formulation represents a safe, effective, and natural alternative to conventional synthetic anti-inflammatory topical preparations.
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